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New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications. Antiproliferative effect of actinomycin D was eliminated by reduced inhibitor level brought about under the influence of exogenous trypsin. However, the results did not show any advantage for the addition of metaproterenol either in respect of enhanced antidepressant effect or a reduced incidence, nature, or severity of side-effects. Increased frequency of HLA–Dw3 in North-American black patients with juvenile onset diabetes.
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